Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.45 |
| ▸ | MAOA | P21397 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064099 | 0.81 | ALDH1A1 (0.46) | MAOBMAOAALDH1A1LMNAGAA | |
| SCHEMBL11064104 | 0.81 | ALDH1A1 (0.46) | MAOBMAOAALDH1A1LMNAGAA | |
| SCHEMBL13518222 | 0.76 | MAOA (0.47) | MAOBMAOAALDH1A1LMNAOPRM1 | |
| SCHEMBL9653163 | 0.76 | CYP19A1 (0.40) | MAOBMAOAALDH1A1LMNAL3MBTL1 | |
| SCHEMBL30312220 | 0.76 | OPRM1 (0.50) | MAOBMAOAALDH1A1LMNAGAA | |
| SCHEMBL1641588 | 0.75 | RAB9A (0.45) | MAOBMAOAALDH1A1LMNAGAA | |
| SCHEMBL2354190 | 0.75 | LMNA (0.41) | MAOBMAOAALDH1A1LMNAGAA | |
| SCHEMBL15778080 | 0.75 | MAOA (0.45) | MAOBMAOAALDH1A1LMNAGAA | |
| SCHEMBL31172182 | 0.74 | SLC6A4 (0.46) | — | |
| SCHEMBL13562892 | 0.74 | MAOB (0.48) | MAOBMAOAOPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676795-B2 | Process to obtain a trifluoromethylating composition | FUNDACIO INSTITUT CATALA D'INVESTIGACIO QUIMICA (ES) | 2017-06-13 | — | — | US | disclosed |
| EP-2678302-B1 | PROCESS TO OBTAIN A TRIFLUOROMETHYLATING COMPOSITION | FUNDACIÓ INST CATALÀ D INVESTIGACIÓ QUÍMICA (ES) | 2016-08-17 | — | — | EP | disclosed |
| US-20140235866-A1 | Process to Obtain a Trifluoromethylating Composition | FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA (ES) | 2014-08-21 | — | — | US | disclosed |
| US-8729320-B2 | Method for producing difluorocyclopropane compound | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-05-20 | — | — | US | disclosed |
| EP-2678302-A1 | PROCESS TO OBTAIN A TRIFLUOROMETHYLATING COMPOSITION | Fundació Institut Català d'Investigació Química (ES) | 2014-01-01 | — | — | EP | disclosed |
| US-20120277458-A1 | METHOD FOR PRODUCING DIFLUOROCYCLOPROPANE COMPOUND | CENTRAL GLASS COMPANY, LIMITED (JP) | 2012-11-01 | — | — | US | disclosed |
| WO-2012113726-A1 | PROCESS TO OBTAIN A TRIFLUOROMETHYLATING COMPOSITION | FUNDACIÓ PRIVADA INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2012-08-30 | — | — | WO | disclosed |
| EP-0253175-B1 | SUBSTITUTED FURAZANS | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |
| US-4853397-A | MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-08-01 | — | — | US | disclosed |
| EP-0253175-A2 | Substituted furazans | BAYER AG (DE) | 1988-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235866-A1 | Process to Obtain a Trifluoromethylating Composition | FLI1, FIP1L1, AFF1 | MAOB 161/4885MAOA 144/4885ALDH1A1 388/4885 |
| US-20120277458-A1 | METHOD FOR PRODUCING DIFLUOROCYCLOPROPANE COMPOUND | FDPS, PFAS, FDFT1 | MAOB 1298/4885MAOA 1500/4885ALDH1A1 658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.