Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543383 | 0.79 | ALDH1A1 (0.47) | SMN1; SMN2MEN1KMT2ATDP1KDM4E | |
| SCHEMBL11069022 | 0.76 | TDP1 (0.57) | SMN1; SMN2MEN1KMT2ATTRTDP1 | |
| SCHEMBL10717379 | 0.72 | ALDH1A1 (0.55) | HTR6MEN1KMT2ATTRALB | |
| SCHEMBL11156706 | 0.72 | PIN1 (0.40) | HTR6SMN1; SMN2MEN1KMT2ATTR | |
| SCHEMBL11091901 | 0.72 | LTA4H (0.55) | SMN1; SMN2MEN1KMT2ATTRALB | |
| SCHEMBL7967638 | 0.71 | ALDH1A1 (0.45) | SMN1; SMN2MEN1KMT2ATDP1KDM4E | |
| SCHEMBL8563304 | 0.70 | HTT (0.39) | SMN1; SMN2MEN1KMT2ATHRBKDM4E | |
| SCHEMBL11067702 | 0.70 | HTR6 (0.57) | HTR6MEN1KMT2ATTRALB | |
| SCHEMBL11154755 | 0.69 | SYK (0.43) | HTR6MEN1KMT2ATTRALB | |
| SCHEMBL2138411 | 0.68 | TDP1 (0.47) | HTR6SMN1; SMN2MEN1KMT2ATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431439-A | PLANT GROWTH INHIBITORS; SELELCTIVE FOR CEREAL CROPS | CIBA-GEIGY CORPORATION (US) | 1984-02-14 | — | — | US | disclosed |
| EP-0035475-B1 | HERBICIDALLY ACTIVE 2-NITRO-5-PHENOXYPHENYL OXAZOLES, OXAZINES, IMIDAZOLES, PYRIMIDINES AND THIAZOLES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1983-11-30 | — | — | EP | disclosed |
| US-4405627-A | ANTISPASMODIC AGENTS; MUSCLE RELAXANTS; LOCAL ANESTHETICS | ITALIANA SCHOUM S.P.A. (IT) | 1983-09-20 | — | — | US | disclosed |
| US-4350519-A | SELECTIVE ACTION, PRE- AND POSTEMERGENCE | CIBA-GEIGY CORPORATION (US) | 1982-09-21 | — | — | US | disclosed |
| EP-0035475-A1 | Herbicidally active 2-nitro-5-phenoxyphenyl oxazoles, oxazines, imidazoles, pyrimidines and thiazoles, their preparation and their use | CIBA-GEIGY AG (CH) | 1981-09-09 | — | — | EP | disclosed |