Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | DRD1 | P21728 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 5/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | MLNR | O43193 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068915 | 0.89 | DRD2 (0.60) | CHRM2HTR1AADRA2ADRD1ADRA1A | |
| Hydrochloric Acid SCHEMBL11066446 | 0.88 | DRD2 (0.59) | CHRM2HTR1AADRA2ADRD1ADRA1A | |
| SCHEMBL11067238 | 0.85 | HRH2 (0.48) | KMT2AALDH1A1TSHRLMNAHRH1 | |
| SCHEMBL11065708 | 0.82 | HTR5A (0.46) | DRD3DRD2HTR2A | |
| SCHEMBL11073339 | 0.81 | DRD2 (0.60) | CHRM2HTR1AADRA2ADRD1ADRA1A | |
| Hydrochloric Acid SCHEMBL11065041 | 0.81 | DRD2 (0.59) | CHRM2HTR1AADRA2ADRD1ADRA1A | |
| SCHEMBL11068301 | 0.78 | MEN1 (0.54) | CHRM2HTR1AADRA2ADRD1ADRA1A | |
| SCHEMBL11066025 | 0.77 | HTR1A (0.50) | CHRM2HTR1AADRA2ADRD1ADRA1A | |
| SCHEMBL11068893 | 0.76 | ALDH1A1 (0.52) | CHRM2HTR1AADRA2ADRD1ADRA1A | |
| SCHEMBL11364041 | 0.76 | DRD2 (0.61) | CHRM2HTR1AADRA2ADRD1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |