Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27573628 | 0.98 | MAPT (0.53) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL19435759 | 0.86 | MAPT (0.43) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL110681 | 0.82 | ALDH1A1 (0.52) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL29534931 | 0.82 | ALDH1A1 (0.52) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL347390 | 0.81 | MAPT (0.59) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL30839714 | 0.81 | MAPT (0.59) | MAPTGAAMAPK1TSHRHTT | |
| Hydrochloric Acid SCHEMBL15486482 | 0.80 | MAPT (0.53) | MAPTGAAMAPK1TSHRHTT | |
| Hydrochloric Acid SCHEMBL10604756 | 0.79 | MAPT (0.57) | MAPTGAAMAPK1TSHRHTT | |
| Benzene SCHEMBL28800866 | 0.78 | CYP1A2 (0.50) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL77823 | 0.78 | KDM4E (0.67) | MAPTGAAMAPK1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 901 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024433-A | naphthalimide-TB compound and synthetic method and application thereof | 江苏师范大学 | 2023-11-10 | — | — | CN | claimed |
| CN-116891478-A | Benzophenone hydrazone-TB derivative and synthetic method and application thereof | 江苏师范大学 | 2023-10-17 | — | — | CN | claimed |
| CN-109153655-B | Novel N-acylurea derivatives and compositions comprising the same for preventing or treating cardiovascular diseases | 高丽大学校产学协力团 | 2022-09-30 | — | — | CN | claimed |
| US-20220194928-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | UNIV KOREA RES & BUS FOUND (KR) | 2022-06-23 | — | — | US | claimed |
| CN-111848633-B | coumarin-Tr baby's base Fe3+ fluorescent probe and preparation method thereof | 江苏师范大学 | 2022-04-12 | — | — | CN | claimed |
| CN-111848633-A | coumarin-Tr star gers' base Fe3+ fluorescent probe and preparation method thereof | 江苏师范大学 | 2020-10-30 | — | — | CN | claimed |
| US-10696611-B2 | Adamantane derivative compound | AMOREPACIFIC CORPORATION (KR) | 2020-06-30 | — | — | US | claimed |
| CN-107522657-B | Compound with PPAR (peroxisome proliferator activated receptor) multiple agonistic activity and preparation method and application thereof | 上海中医药大学 | 2020-06-26 | — | — | CN | claimed |
| US-20190119261-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2019-04-25 | — | — | US | claimed |
| CN-109320403-A | A kind of preparation method of 2,5- dibromophenol | 常州大学 | 2019-02-12 | — | — | CN | claimed |
| CN-105330584-B | The preparation method of 4 methoxyl group isatin | 常州工程职业技术学院 | 2017-10-10 | — | — | CN | claimed |
| US-20170283347-A1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | AMOREPACIFIC CORPORATION (KR) | 2017-10-05 | — | — | US | claimed |
| EP-3187486-A1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | Amorepacific Corporation (KR) | 2017-07-05 | — | — | EP | claimed |
| CN-102993022-A | Preparation method of bromoaniline | UNIV SHANGHAI ENG SCIENCE | 2013-03-27 | — | — | CN | claimed |
| US-20260124309-A1 | STAT6 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-05-07 | — | — | US | disclosed |
| EP-4083031-B1 | QUINOLINE COMPOUND AND APPLICATION THEREOF AS FGFR4 KINASE INHIBITOR | SKYRUN PHARMA CO LTD (CN) | 2026-04-22 | — | — | EP | disclosed |
| US-12552772-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. (US) | 2026-02-17 | — | — | US | disclosed |
| US-4882354-A | N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1989-11-21 | — | — | US | disclosed |
| EP-0321431-A1 | N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1989-06-21 | — | — | EP | disclosed |
| EP-0251380-A2 | 2- (5-phenyl-2-furanyl) imidazoles useful as cardiotonic agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696611-B2 | Adamantane derivative compound | ADAM8, BACE1, CYP17A1 | MAPT 1527/4885GAA 743/4885MAPK1 2937/4885 |
| US-20170283347-A1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | ADAM8, CYP17A1, ADAM10 | MAPT 1766/4885GAA 1163/4885MAPK1 2795/4885 |
| US-20260124309-A1 | STAT6 DEGRADERS AND USES THEREOF | STAT6, NCOR2, NCOR1 | MAPT 4555/4885GAA 4235/4885MAPK1 2997/4885 |
| US-12552772-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | YAP1, TEAD3, TEAD2 | MAPT 1955/4885GAA 4357/4885MAPK1 899/4885 |
| US-20190119261-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | TLN1, TNNI3, PTK2 | MAPT 3132/4885GAA 2381/4885MAPK1 2970/4885 |
| US-20220194928-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | TLN1, TNNI3, PTK2 | MAPT 3132/4885GAA 2381/4885MAPK1 2970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.