Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GGT1 | P19440 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232205 | 0.88 | ACLY (0.52) | ACLYACACBACACAALDH1A1CYP1A2 | |
| SCHEMBL154712 | 0.86 | ACLY (0.55) | ACLYACACBACACACYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL561986 | 0.86 | ACLY (0.50) | ACLYACACBACACACYP1A2GGT1 | |
| Hydrochloric Acid SCHEMBL2867978 | 0.86 | ACLY (0.50) | ACLYACACBACACACYP1A2GGT1 | |
| SCHEMBL3293803 | 0.84 | LMNA (0.38) | ALDH1A1CYP1A2KMT2AMEN1ALOX15 | |
| SCHEMBL250911 | 0.84 | ACLY (0.59) | ACLYACACBACACACYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL562371 | 0.84 | ACLY (0.53) | ACLYACACBACACACYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL621977 | 0.84 | ACLY (0.53) | ACLYACACBACACACYP1A2KMT2A | |
| Trifluoroacetic Acid SCHEMBL4530228 | 0.82 | NOS1 (0.36) | ACLYALDH1A1CYP1A2KMT2AGGT1 | |
| Hydrochloric Acid SCHEMBL561963 | 0.82 | ACLY (0.57) | ACLYACACBACACACYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3018126-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2016-05-11 | — | — | EP | disclosed |
| US-8153716-B2 | Dispersant for an aqueous dispersion of positively charged or chargeable solid particulates which comprises a compound having an anchoring moiety linked to a polymeric hydrophilic moiety; inkjet recording element | EASTMAN KODAK COMPANY (US) | 2012-04-10 | — | — | US | disclosed |
| US-8063132-B2 | Coating composition comprising boehmite particles and one or more dispersants and a method of coating a substrate using said coating composition | EASTMAN KODAK COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| EP-1933761-B1 | INFLATABLE BIFURCATION STENT | BOSTON SCIENT LTD (BB) | 2010-11-24 | — | — | EP | disclosed |
| US-7785365-B2 | Endovascular apparatus | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-7731741-B2 | Inflatable bifurcation stent | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-06-08 | — | — | US | disclosed |
| US-7491230-B2 | Endovascular apparatus | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2009-02-17 | — | — | US | disclosed |
| EP-1933761-A1 | INFLATABLE BIFURCATION STENT | Boston Scientific Limited (BB) | 2008-06-25 | — | — | EP | disclosed |
| US-20080145546-A1 | Dispersant For Reducing Viscosity Of Particulate Solids | FPC INC. | 2008-06-19 | — | — | US | disclosed |
| US-20080090012-A1 | Aqueous boehmite particles of a hydrophilic polymer having a linked anchoring moiety which contains acid(s) and/or hydroxy(s); the polymeric moiety has a lower affinity for a boehmite surface than the anchoring moiety; mercaptosuccinic acid-modified polyacrylamide; ink jet; paper coating; gloss porousity | KODAK PHILIPPINES LTD. | 2008-04-17 | — | — | US | disclosed |
| US-20030220684-A1 | Endovascular apparatus | SCIMED LIFE SYSTEMS, INC. (US) | 2003-11-27 | — | — | US | disclosed |
| US-20030208257-A1 | Endovascular apparatus | HOLMAN THOMAS J (US) | 2003-11-06 | — | — | US | disclosed |
| US-20030083738-A1 | Endovascular apparatus | HOLMAN THOMAS J (US) | 2003-05-01 | — | — | US | disclosed |
| US-20020040235-A1 | Endovascular apparatus | HOLMAN THOMAS J (US) | 2002-04-04 | — | — | US | disclosed |
| US-6319276-B1 | Endovascular apparatus | SCIMED LIFE SYSTEMS, INC. | 2001-11-20 | — | — | US | disclosed |
| US-6059823-A | Endovascular apparatus | SCIMED LIFE SYSTEMS, INC. (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0959810-A1 | ENDOVASCULAR APPARATUS | SciMed Life Systems, Inc. (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5871537-A | Endovascular apparatus | SCIMED LIFE SYSTEMS, INC. (US) | 1999-02-16 | — | — | US | disclosed |
| WO-1997029716-A1 | ENDOVASCULAR APPARATUS | SCIMED LIFE SYSTEMS, INC. (US) | 1997-08-21 | — | — | WO | disclosed |
| US-4403037-A | COATED WITH VIRUS ANTIGEN, STABILIZED | AMERICAN HOECHST CORPORATION | 1983-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090012-A1 | Aqueous boehmite particles of a hydrophilic polymer having a linked anchoring moiety which contains acid(s) and/or hydroxy(s); the polymeric moiety has a lower affinity for a boehmite surface than the anchoring moiety; mercaptosuccinic acid-modified polyacrylamide; ink jet; paper coating; gloss porousity | CD44, MPST, BHMT2 | ACLY 4406/4885ACACB 4800/4885ACACA 4486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.