Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16989819 | 0.75 | RIPK1 (0.48) | SMN1; SMN2ALDH1A1KMT2ALMNANPC1 | |
| SCHEMBL1140947 | 0.75 | SMN1; SMN2 (0.55) | ALOX5SMN1; SMN2LTA4HALDH1A1MAPK1 | |
| SCHEMBL9324850 | 0.75 | SMN1; SMN2 (0.55) | ALOX5SMN1; SMN2LTA4HALDH1A1MAPK1 | |
| SCHEMBL1303146 | 0.74 | LTA4H (0.62) | ALOX5SMN1; SMN2LTA4HALDH1A1KMT2A | |
| SCHEMBL14350237 | 0.73 | SMN1; SMN2 (0.50) | ALOX5SMN1; SMN2LTA4HALDH1A1MAPK1 | |
| SCHEMBL11069887 | 0.73 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1KMT2ATDP1POLB | |
| SCHEMBL5176893 | 0.72 | BCHE (0.57) | ALOX5SMN1; SMN2LTA4HALDH1A1MAPK1 | |
| SCHEMBL2238587 | 0.72 | ALOX5 (0.49) | ALOX5SMN1; SMN2LTA4HALDH1A1MAPK1 | |
| SCHEMBL4137813 | 0.72 | HDAC3 (0.51) | ALOX5SMN1; SMN2LTA4HALDH1A1MAPK1 | |
| SCHEMBL4321470 | 0.71 | SMN1; SMN2 (0.51) | ALOX5SMN1; SMN2LTA4HALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435322-A | Heterocyclic compounds containing an alkoxycarbonyl and a substituted methyl group | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-03-06 | — | — | US | disclosed |