Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070853 | 0.83 | ALDH1A1 (0.39) | MAPTSMN1; SMN2LMNATSHRPKM | |
| SCHEMBL11077351 | 0.82 | HSP90AA1 (0.40) | MAPTSMN1; SMN2LMNAHTTRAB9A | |
| SCHEMBL10996595 | 0.73 | TSHR (0.55) | MAPTSMN1; SMN2HTTTSHRHPGD | |
| SCHEMBL11168208 | 0.72 | ALDH1A1 (0.36) | MAPTSMN1; SMN2LMNAHTTTSHR | |
| SCHEMBL10831575 | 0.70 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2LMNATSHRNPC1 | |
| SCHEMBL28860063 | 0.70 | SMN1; SMN2 (0.60) | MAPTALOX12MGLLSMN1; SMN2LMNA | |
| SCHEMBL11160025 | 0.69 | ACHE (0.46) | MAPTLMNATSHRRAB9AALDH1A1 | |
| SCHEMBL11176919 | 0.69 | AKR1C3 (0.44) | MAPTSMN1; SMN2LMNAHTTGAA | |
| SCHEMBL10800979 | 0.69 | ACHE (0.42) | MAPTLMNATSHRRAB9AALDH1A1 | |
| SCHEMBL26757997 | 0.69 | MGLL (0.54) | MAPTALOX12MGLLSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4480105-A | PHOTOCROSSLINKING POLYMERS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4385182-A | SENSITIZERS OR PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |
| US-4363917-A | SENSITIZERS FOR PHOTOCROSSLINKABLE POLYMERS; PHOTOPOLYMERIZATION INITIATORS | CIBA-GEIGY CORPORATION (US) | 1982-12-14 | — | — | US | disclosed |