Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070828 | 0.85 | OPRL1 (0.47) | SIGMAR1CCR3 | |
| SCHEMBL11072709 | 0.84 | MEN1 (0.47) | SIGMAR1DRD2DRD3HTR7HTR1A | |
| SCHEMBL10568767 | 0.84 | SIGMAR1 (0.58) | SIGMAR1DRD2DRD3CHRM1CHRM2 | |
| SCHEMBL11071740 | 0.78 | HTR7 (0.50) | SIGMAR1DRD2DRD3DRD4HTR7 | |
| SCHEMBL11070967 | 0.77 | DRD2 (0.53) | SIGMAR1DRD2DRD3DRD4HTR7 | |
| SCHEMBL11062798 | 0.76 | CHRM2 (0.60) | DRD2DRD3CHRM1CHRM2CHRM4 | |
| SCHEMBL11066992 | 0.75 | ABCB1 (0.56) | — | |
| SCHEMBL11066798 | 0.73 | HTR7 (0.42) | SIGMAR1DRD2DRD3DRD4HTR7 | |
| SCHEMBL11317579 | 0.73 | L3MBTL1 (0.45) | S1PR5DRD2DRD3CHRM1CHRM2 | |
| SCHEMBL10568199 | 0.73 | SIGMAR1 (0.58) | SIGMAR1DRD2DRD3CHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |