Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NAMPT | P43490 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083276 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL11079972 | 0.82 | ALDH1A1 (0.59) | TSHRALDH1A1MEN1KMT2ACYP11B2 | |
| SCHEMBL11075878 | 0.82 | NAMPT (0.48) | TSHRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL11078900 | 0.81 | NPC1 (0.60) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11072104 | 0.79 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL11072102 | 0.79 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL11077042 | 0.79 | LMNA (0.56) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL11079424 | 0.78 | LMNA (0.56) | MEN1KMT2AMAPK1POLBSMN1; SMN2 | |
| SCHEMBL18132518 | 0.78 | ALDH1A1 (0.72) | TSHRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL9456935 | 0.77 | ABCC9 (0.57) | ALDH1A1KDM4EHPGDKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119428-A2 | Biscarboxamides for treating diseases, and process for their preparation | BAYER AG (DE) | 1984-09-26 | — | — | EP | disclosed |