Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253367 | 0.81 | EPHX1 (0.43) | HTTEPHX1EPHX2NPC1MEN1 | |
| SCHEMBL11253376 | 0.76 | LMNA (0.43) | HTTEPHX1EPHX2MEN1KMT2A | |
| SCHEMBL10673457 | 0.74 | RORC (0.42) | HTTEPHX1EPHX2NPC1MEN1 | |
| SCHEMBL11036774 | 0.74 | L3MBTL1 (0.44) | HTTMEN1KMT2ALMNAPOLB | |
| SCHEMBL10777200 | 0.70 | MAPT (0.64) | HTTNPC1MEN1KMT2ALMNA | |
| SCHEMBL11063440 | 0.69 | MEN1 (0.65) | HTTNPC1MEN1KMT2ALMNA | |
| SCHEMBL11134452 | 0.69 | PNLIP (0.63) | HTTMEN1KMT2AMAPT | |
| SCHEMBL11007148 | 0.69 | KDM4E (0.43) | EPHX1EPHX2NPC1MEN1KMT2A | |
| SCHEMBL10756283 | 0.68 | TAS1R3 (0.51) | HTTNPC1MEN1KMT2ALMNA | |
| SCHEMBL11460862 | 0.68 | ESRRA (0.51) | EPHX1EPHX2MEN1KMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459238-A | N-Arylthiolcarbamates, herbicides containing them, and processes for combating the growth of unwanted plants with these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1984-07-10 | — | — | US | claimed |
| EP-0019759-B1 | N-ARYLTHIOLCARBAMATES, HERBICIDES CONTAINING THEM AND PROCESS FOR COMBATING UNDESIRABLE PLANT GROWTH THEREWITH | BASF Aktiengesellschaft (DE) | 1982-02-10 | — | — | EP | claimed |