Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10673457 | 0.76 | RORC (0.42) | KDM4ETSHRLMNAMAPTCYP3A4 | |
| SCHEMBL8293311 | 0.71 | TSHR (0.50) | KDM4ETSHREPHX2 | |
| SCHEMBL8295723 | 0.70 | ALDH1A1 (0.46) | KDM4ETSHRLMNAMAPTSMN1; SMN2 | |
| SCHEMBL318346 | 0.70 | HSD17B10 (0.56) | KDM4ETSHRCYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL8295689 | 0.70 | OPRK1 (0.44) | KDM4ELMNASMN1; SMN2RORCEPHX1 | |
| SCHEMBL436854 | 0.69 | IDO1 (0.50) | KDM4ELMNATP53CYP3A4MEN1 | |
| SCHEMBL23709481 | 0.69 | KMT2A (0.59) | KDM4ETSHRLMNAMAPTCYP3A4 | |
| SCHEMBL11077635 | 0.69 | HTT (0.41) | KDM4ETSHRLMNAMAPTCYP3A4 | |
| SCHEMBL10777200 | 0.69 | MAPT (0.64) | KDM4ELMNATP53MAPTSMN1; SMN2 | |
| SCHEMBL1906950 | 0.68 | RORC (0.54) | KDM4ECNR1MAPTCYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4494983-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1985-01-22 | — | — | US | disclosed |
| US-4422864-A | Cyclohexanedione derivatives, their preparation and herbicides containing them | BASF AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | disclosed |