Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.36 |
| ▸ | NAAA | Q02083 | 6/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079057 | 0.92 | EPHX1 (0.44) | FKBP1ANAAAEPHX1 | |
| SCHEMBL11070610 | 0.92 | EPHX1 (0.44) | FKBP1ANAAAEPHX1 | |
| SCHEMBL11068141 | 0.90 | FKBP1A (0.39) | FKBP1ANAAAEPHX1SMN1; SMN2NPC1 | |
| SCHEMBL11074544 | 0.89 | ALDH1A1 (0.35) | FKBP1ANAAAEPHX1SMN1; SMN2NPC1 | |
| SCHEMBL11079388 | 0.86 | EPHX1 (0.41) | FKBP1ANAAAEPHX1 | |
| SCHEMBL11077066 | 0.86 | CYP4F2 (0.38) | NAAAEPHX1 | |
| SCHEMBL11070035 | 0.85 | NAAA (0.36) | FKBP1ANAAAEPHX1SMN1; SMN2NPC1 | |
| SCHEMBL11072205 | 0.85 | NAAA (0.36) | FKBP1ANAAAEPHX1SMN1; SMN2NPC1 | |
| SCHEMBL11073121 | 0.83 | ABCB11 (0.40) | NAAAEPHX1 | |
| SCHEMBL11070926 | 0.83 | EPHX1 (0.41) | FKBP1ANAAAEPHX1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430339-A | PROPHYLAXIS, METABOLISM, GLUCOSE, FATS, HYPOGLYCEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |
| WO-1982000822-A1 | SUBSTITUTED OXIRANECARBOXYLIC ACIDS,THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | EISTETTER K | 1982-03-18 | — | — | WO | disclosed |