Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504833 | 0.86 | PDK2 (0.46) | PDK2NPC1RAB9AKMT2AGRM5 | |
| SCHEMBL28704926 | 0.79 | RAB9A (0.48) | BCAT2NPC1RAB9AKMT2AGRM5 | |
| SCHEMBL30823709 | 0.75 | HCRTR1 (0.49) | BCAT2KDM4ENPC1RAB9AGRM5 | |
| SCHEMBL2647877 | 0.75 | PDK2 (0.50) | PDK2KDM4EKMT2AGRM5MAPK1 | |
| SCHEMBL20073445 | 0.73 | TYK2 (0.46) | PDK2ALDH1A1MAPT | |
| SCHEMBL4927936 | 0.72 | MKNK1 (0.44) | NPC1RAB9ACYP1A2TP53 | |
| SCHEMBL9823051 | 0.72 | PDK2 (0.42) | PDK2 | |
| SCHEMBL17080330 | 0.72 | BCAT2 (0.46) | BCAT2KDM4ENPC1RAB9AGRM5 | |
| SCHEMBL3343751 | 0.72 | WNT1 (0.39) | NPC1RAB9AKMT2ATP53TSHR | |
| SCHEMBL30964842 | 0.71 | BCAT2 (0.53) | BCAT2KDM4ENPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474792-A | N-Tetrazolyl benzamides and anti-allergic use thereof | RIKER LABORATORIES, INC. (US) | 1984-10-02 | — | — | US | disclosed |
| US-4432986-A | N-(TETRAZOL-5-YL)-(DIBENZOTHIOPHENE-, OR DIBENZOFURAN-, OR 1,3-BEZODIOXOLE-, OR NAPHTHALENE-)-4-CARBOXAMIDE | RIKER LABORATORIES, INC. (US) | 1984-02-21 | — | — | US | disclosed |