Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALKBH3 | Q96Q83 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14942695 | 0.81 | ALKBH3 (0.45) | ALDH1A1KMT2ATSHRMEN1LMNA | |
| SCHEMBL9879442 | 0.80 | ALDH1A1 (0.74) | POLBALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL14029140 | 0.79 | ALKBH3 (0.43) | POLBALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL10857015 | 0.79 | LMNA (0.70) | POLBALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL15359657 | 0.78 | TP53 (0.46) | ALDH1A1KMT2ALMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL10048197 | 0.75 | ADORA2A (0.50) | POLBALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL9829434 | 0.74 | XDH (0.49) | POLBALDH1A1LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL10735952 | 0.72 | ALDH1A1 (0.73) | POLBALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL9879042 | 0.72 | HTT (0.40) | ALDH1A1TSHRHTTCYP2C9CYP2C19 | |
| SCHEMBL9878574 | 0.72 | POLB (0.61) | POLBALDH1A1KMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4470985-A | HISTAMINE H-2 ANTAGONISTS | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1984-09-11 | — | — | US | disclosed |