Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879325 | 0.85 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1CYP2C9CYP2C19LMNA | |
| SCHEMBL11079720 | 0.80 | POLB (0.56) | ALDH1A1L3MBTL1CYP2C9CYP2C19LMNA | |
| SCHEMBL9879389 | 0.78 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1LMNAPOLBTDP1 | |
| SCHEMBL9878778 | 0.71 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1CYP2C9CYP2C19LMNA | |
| SCHEMBL9879475 | 0.69 | POLB (0.71) | ALDH1A1LMNAPOLBMAPTRAB9A | |
| SCHEMBL10735952 | 0.69 | ALDH1A1 (0.73) | ALDH1A1L3MBTL1CYP2C9CYP2C19LMNA | |
| SCHEMBL20470604 | 0.68 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1CYP2C19HCAR2TDP1 | |
| SCHEMBL9829434 | 0.67 | XDH (0.49) | ALDH1A1L3MBTL1CYP2C9CYP2C19LMNA | |
| SCHEMBL11458923 | 0.66 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1HCAR2RAB9A | |
| SCHEMBL10857015 | 0.64 | LMNA (0.70) | ALDH1A1L3MBTL1CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018887-A1 | DIAMINOPYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-12-12 | — | — | WO | disclosed |