SCHEMBL11086178

SCHEMBL11086178

COC12CC3CC(CC([C]=O)(C3)C1)C2

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.34
DPP4 P27487 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6901718 0.79 NPSR1 (0.39) NPSR1DPP4
SCHEMBL692515 0.79 LMNA (0.30)
SCHEMBL10415070 0.71 TSHR (0.38) NPSR1DPP4
SCHEMBL10415069 0.69 NPSR1 (0.33) NPSR1DPP4
SCHEMBL11091802 0.69 PKM (0.47) DPP4
SCHEMBL11088099 0.69 DPP4 (0.32) DPP4
SCHEMBL11088195 0.69 LMNA (0.31)
SCHEMBL11089627 0.69 THRB (0.42)
SCHEMBL3360868 0.69 GRIN1 (0.48) NPSR1DPP4
SCHEMBL14141112 0.69 PKM (0.47) NPSR1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0028936-B1 4-CARBAMOYLIMIDAZOL-5-OL DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-04-11 EP claimed
US-4332806-A Antitumor and immunosuppresive 4-carbamoyl imidazolium-5-olate derivatives, pharmaceutical composition and production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-06-01 US claimed