SCHEMBL11088099

SCHEMBL11088099

O=[C]C12CC3CC(CC(F)(C3)C1)C2

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL692515 0.84 LMNA (0.30)
SCHEMBL2574454 0.75 GRIN2D (0.33) DPP4
SCHEMBL11089627 0.74 THRB (0.42)
SCHEMBL11091802 0.74 PKM (0.47) DPP4
SCHEMBL11090307 0.74
SCHEMBL465574 0.73 GRIN2D (0.38)
SCHEMBL31226224 0.69 DYRK3 (0.32) DPP4
SCHEMBL6152600 0.69 PKM (0.47)
SCHEMBL7517207 0.67
SCHEMBL15922467 0.65 PKM (0.52) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0028936-B1 4-CARBAMOYLIMIDAZOL-5-OL DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-04-11 EP claimed
US-4332806-A Antitumor and immunosuppresive 4-carbamoyl imidazolium-5-olate derivatives, pharmaceutical composition and production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-06-01 US claimed
EP-0028936-A2 4-Carbamoylimidazol-5-ol derivatives, their production and pharmaceutical compositions containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-05-20 EP claimed