SCHEMBL8772279

SCHEMBL8772279

Cc1cc(C(C)(C)C)c(Cc2ccc(O)cc2)c(C(C)(C)C)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.49
SMN1; SMN2 Q16637 3/20 0.48
TYR P14679 3/20 0.48
ALDH1A1 P00352 2/20 0.48
CA2 P00918 1/20 0.48
POLB P06746 1/20 0.48
CYP2C9 P11712 4/20 0.47
CYP2C19 P33261 3/20 0.47
HIF1A Q16665 3/20 0.47
ESR1 P03372 3/20 0.45
ESR2 Q92731 2/20 0.45
IDH1 O75874 2/20 0.44
HSD17B10 Q99714 2/20 0.42
CYP2D6 P10635 1/20 0.42
LMNA P02545 2/20 0.41
NR1I2 O75469 1/20 0.41
MIF P14174 1/20 0.41
ALOX15 P16050 1/20 0.41
HTT P42858 1/20 0.41
NFE2L2 Q16236 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9007185 0.89 LMNA (0.48) HSPA5SMN1; SMN2TYRALDH1A1CYP2C9
SCHEMBL29022939 0.81 CA2 (0.48) TYRALDH1A1CA2CYP2C9ESR1
SCHEMBL11087884 0.81 THRA (0.44) HSPA5TYRALDH1A1CYP2C9CYP2C19
SCHEMBL8377432 0.81 HSPA5 (0.72) HSPA5SMN1; SMN2TYRALDH1A1CA2
SCHEMBL292111 0.78 LMNA (0.42) HSPA5TYRALDH1A1CYP2C9CYP2C19
SCHEMBL15799777 0.77 THRB (0.57) ALDH1A1POLBESR1ESR2IDH1
SCHEMBL30621822 0.77 ALDH1A1 (0.53) HSPA5SMN1; SMN2TYRALDH1A1CA2
SCHEMBL28945586 0.77 ALDH1A1 (0.53) HSPA5SMN1; SMN2TYRALDH1A1CA2
SCHEMBL4988778 0.77 THRA (0.38) HSPA5TYRALDH1A1CYP2C9ESR1
Butylated Hydroxytoluene SCHEMBL9619750 0.77 CA2 (0.82) HSPA5SMN1; SMN2TYRALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed