Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.78 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.73 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.73 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.72 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602214 | 0.86 | ROCK2 (0.71) | NAMPTROCK2ROCK1SMN1; SMN2RAB9A | |
| SCHEMBL5384036 | 0.85 | ROCK2 (0.76) | NAMPTROCK2ROCK1SMN1; SMN2RAB9A | |
| Nicotinanilide SCHEMBL352439 | 0.85 | LMNA (0.83) | NAMPTROCK2ROCK1SMN1; SMN2RAB9A | |
| Nicotinanilide SCHEMBL29067673 | 0.85 | LMNA (0.83) | NAMPTROCK2ROCK1SMN1; SMN2RAB9A | |
| SCHEMBL14880208 | 0.85 | ROCK2 (1.00) | NAMPTROCK2ROCK1SMN1; SMN2RAB9A | |
| SCHEMBL31006494 | 0.84 | PTGS2 (0.67) | NAMPTCYP11B1CYP11B2SMN1; SMN2RAB9A | |
| SCHEMBL28871747 | 0.84 | PTGS2 (0.67) | NAMPTCYP11B1CYP11B2SMN1; SMN2RAB9A | |
| SCHEMBL4965181 | 0.84 | TSHR (0.71) | NAMPTCYP11B1CYP11B2SMN1; SMN2RAB9A | |
| SCHEMBL10978857 | 0.84 | CYP11B1 (1.00) | NAMPTCYP11B1CYP11B2SMN1; SMN2RAB9A | |
| SCHEMBL1971026 | 0.84 | NAMPT (0.78) | NAMPTROCK2ROCK1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101857610-A | Palladium complex and preparation method thereof | SHENYANG INST OF CHEMICAL TECH | 2010-10-13 | — | — | CN | disclosed |
| EP-0033183-B1 | PHENYLIMINOMETHYL-3-PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-07-04 | — | — | EP | disclosed |
| EP-0008145-B1 | USE OF PHENYLIMINOMETHYLPYRIDINE DERIVATIVES AS FUNGICIDES AND PLANT GROWTH REGULANTS COMPOSITIONS CONTAINING SUCH DERIVATIVES AND PHENYLIMINOMETHYLPYRIDINE DERIVATIVES AND THEIR PREPARATION | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-02-01 | — | — | EP | disclosed |
| EP-0033183-A2 | Phenyliminomethyl-3-pyridine derivatives, their preparation and use | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-08-05 | — | — | EP | disclosed |
| US-4281134-A | FUNGICIDES, PLANT GROWTH REGULATORS | SHELL OIL COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| EP-0008145-A2 | Use of phenyliminomethylpyridine derivatives as fungicides and plant growth regulants compositions containing such derivatives and phenyliminomethylpyridine derivatives and their preparation | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-02-20 | — | — | EP | disclosed |