Nicotinanilide

Nicotinanilide

SCHEMBL352439

O=C(Nc1ccccc1)c1cccnc1

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.83
HIF1A Q16665 1/20 0.83
KCNK3 O14649 1/20 0.82
NAMPT P43490 3/20 0.81
ROCK2 O75116 1/20 0.81
ROCK1 Q13464 1/20 0.81
ALDH1A1 P00352 2/20 0.69
RAB9A P51151 5/20 0.68
NPC1 O15118 4/20 0.68
SMN1; SMN2 Q16637 3/20 0.68
KMT2A Q03164 2/20 0.68
MEN1 O00255 1/20 0.68
TP53 P04637 1/20 0.68
GAA P10253 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
CYP3A4 P08684 1/20 0.66
HTT P42858 1/20 0.66
JAK2 O60674 1/20 0.66
TYK2 P29597 1/20 0.66
PIM1 P11309 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nicotinanilide SCHEMBL29067673 1.00 LMNA (0.83) LMNAHIF1AKCNK3NAMPTROCK2
Nicotinanilide SCHEMBL8155304 0.98 LMNA (0.81) LMNAHIF1AKCNK3NAMPTROCK2
Nicotinanilide SCHEMBL27369687 0.94 LMNA (0.73) LMNAHIF1AKCNK3NAMPTROCK2
SCHEMBL1571386 0.91 LMNA (1.00) LMNAHIF1AKCNK3NAMPTROCK2
Nicotinanilide SCHEMBL27980002 0.91 LMNA (0.69) LMNAHIF1AKCNK3NAMPTROCK2
SCHEMBL167081 0.89 NAMPT (1.00) LMNAHIF1AKCNK3NAMPTRAB9A
SCHEMBL14880208 0.89 ROCK2 (1.00) LMNAHIF1AKCNK3NAMPTROCK2
SCHEMBL7329481 0.88 ROCK2 (0.73) LMNAHIF1AKCNK3NAMPTROCK2
Hydrochloric Acid SCHEMBL27890956 0.88 NAMPT (0.97) LMNAHIF1AKCNK3NAMPTRAB9A
SCHEMBL28276093 0.87 NPC1 (0.70) LMNAHIF1AKCNK3NAMPTROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 838 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4687829-A1 COMPOSITION FOR CARING FOR KERATIN MATERIALS L'OREAL (FR) 2026-02-11 EP claimed
US-20250381116-A1 SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME OREAL (FR) 2025-12-18 US claimed
US-20250161201-A1 COSMETIC COMPOSITION THE BOOTS COMPANY PLC (GB) 2025-05-22 US claimed
WO-2025091239-A1 COMPOSITION IN THE FORM OF OIL-IN-WATER EMULSION L'OREAL (FR) 2025-05-08 WO claimed
WO-2025091220-A2 COMPOSITION IN THE FORM OF OIL-IN-WATER EMULSION L'OREAL (FR) 2025-05-08 WO claimed
EP-4543408-A1 SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME L'OREAL (FR) 2025-04-30 EP claimed
EP-4479146-A1 COSMETIC COMPOSITION The Boots Company PLC (GB) 2024-12-25 EP claimed
WO-2024197798-A1 COMPOSITION FOR CARING FOR KERATIN MATERIALS L'OREAL (FR) 2024-10-03 WO claimed
CN-118252153-A Pond cleaning agent for aquaculture and preparation method thereof 江苏牧王药业有限公司 2024-06-28 CN claimed
WO-2024045013-A1 COMPOSITION FOR CARING FOR THE SKIN L'OREAL (FR) 2024-03-07 WO claimed
CN-1558901-A Crystalline hydrates of nicotinic acid anilide and benzoyl anilide derivatives �����ɷ� 2004-12-29 CN claimed
US-20040249164-A1 Crystalline hydrates of nicotinic acid anilide and benzoyl anilide derivatives BASF AKTIENGESELLSCHAFT (DE) 2004-12-09 US claimed
EP-1319336-B1 Method of preparation of solvent-free suspensions BASF AG (DE) 2004-06-23 EP claimed
WO-2004046113-A2 PYRIDINE N-OXIDE COMPOUNDS AS PHOSPHODIESTERASE 4 INHIBITORS MEMORY PHARMACEUTICALS CORPORATION (US) 2004-06-03 WO claimed
EP-1367985-A2 ANHYDROUS ANTIPERSPIRANT AND DEODORANT COMPOSITIONS CONTAINING A SOLID, WATER-SOLUBLE, SKIN ACTIVE AGENT THE PROCTER & GAMBLE COMPANY (US) 2003-12-10 EP claimed
EP-0896522-B1 METHODS OF REGULATING SKIN APPEARANCE WITH VITAMIN B 3 COMPOUND PROCTER & GAMBLE (US) 2003-10-22 EP claimed
US-20030148887-A1 Process for the preparation of solvent-free suspensions BASF AKTIENGESELLSCHAFT (DE) 2003-08-07 US claimed
WO-2002069916-A2 ANHYDROUS ANTIPERSPIRANT AND DEODORANT COMPOSITIONS CONTAINING A SOLID, WATER-SOLUBLE, SKIN ACTIVE AGENT THE PROCTER & GAMBLE COMPANY (US) 2002-09-12 WO claimed
US-6383476-B1 Anhydrous antiperspirant and deodorant compositions containing a solid, water-soluble, skin active agent THE PROCTER & GAMBLE COMPANY 2002-05-07 US claimed
CN-1123083-A Method for increasing yield of soybean SUMITOMO CHEMICAL CO (JP) 1996-05-29 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040249164-A1 Crystalline hydrates of nicotinic acid anilide and benzoyl anilide derivatives NAPRT, NAMPT, NME1 LMNA 2681/4885HIF1A 3879/4885KCNK3 4378/4885
US-20250161201-A1 COSMETIC COMPOSITION CYP19A1, SHBG, HSD17B11 LMNA 3019/4885HIF1A 2176/4885KCNK3 520/4885
US-20030148887-A1 Process for the preparation of solvent-free suspensions MLN, SAMM50, SOST LMNA 2232/4885HIF1A 4487/4885KCNK3 4166/4885
US-20250381116-A1 SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME TBCB, CCNB3, CYP24A1 LMNA 3917/4885HIF1A 4367/4885KCNK3 2693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.