Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14768692 | 0.89 | SLC6A7 (0.51) | SLC6A7KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL14224744 | 0.84 | CKS1B (0.53) | SLC6A7KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL11077602 | 0.80 | ME2 (0.57) | SLC6A7KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL14411664 | 0.79 | SLC6A7 (0.54) | SLC6A7KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL11080396 | 0.79 | POLB (0.50) | SLC6A7KDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL22481434 | 0.78 | SLC6A7 (0.53) | SLC6A7KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL3332171 | 0.78 | HRH3 (0.58) | L3MBTL1KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL16596173 | 0.77 | ITGB3 (0.62) | GNAI3GNAI1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL23244226 | 0.77 | ME2 (0.71) | L3MBTL1KMT2AMEN1TDP1KDM4E | |
| SCHEMBL13073553 | 0.76 | SLC6A7 (0.57) | L3MBTL1SLC6A7KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439606-A | ANTICHOLESTEROL, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | claimed |