⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11451613 | 0.79 | PKM (0.30) | — | |
| SCHEMBL692515 | 0.79 | LMNA (0.30) | — | |
| SCHEMBL11088099 | 0.74 | DPP4 (0.32) | — | |
| SCHEMBL6003457 | 0.69 | PKM (0.47) | — | |
| SCHEMBL12934488 | 0.69 | TSHR (0.37) | — | |
| SCHEMBL11091802 | 0.69 | PKM (0.47) | — | |
| SCHEMBL11089627 | 0.69 | THRB (0.42) | — | |
| SCHEMBL11090309 | 0.69 | — | — | |
| SCHEMBL890623 | 0.69 | GRIN2D (0.38) | — | |
| SCHEMBL465574 | 0.69 | GRIN2D (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028936-B1 | 4-CARBAMOYLIMIDAZOL-5-OL DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-04-11 | — | — | EP | claimed |