Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 5/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517207 | 0.87 | — | — | |
| SCHEMBL8748843 | 0.86 | — | — | |
| SCHEMBL692515 | 0.82 | LMNA (0.30) | LMNASMN1; SMN2 | |
| SCHEMBL2746527 | 0.73 | ALDH1A1 (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11091802 | 0.73 | PKM (0.47) | ALDH1A1 | |
| SCHEMBL11088099 | 0.73 | DPP4 (0.32) | — | |
| SCHEMBL11089627 | 0.73 | THRB (0.42) | THRBGAA | |
| SCHEMBL1821165 | 0.71 | — | — | |
| SCHEMBL4119668 | 0.69 | LMNA (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL10011924 | 0.69 | GRIN2D (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2424 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239508-B | Preparation method of aryl thioimine compound | 岭南师范学院 | 2024-06-21 | — | — | CN | claimed |
| CN-116178230-B | Method for preparing thioimine compound through non-oxidation | 岭南师范学院 | 2024-06-21 | — | — | CN | claimed |
| CN-117069645-A | Tryptophan and C2 alkylation modification method for tryptophan-containing polypeptide | 兰州大学 | 2023-11-17 | — | — | CN | claimed |
| US-20230210834-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2023-07-06 | — | — | US | claimed |
| CN-116178230-A | Method for preparing thioimine compound through non-oxidation | 岭南师范学院 | 2023-05-30 | — | — | CN | claimed |
| US-11655225-B2 | Antimycobacterial heterocyclic amides | CRESTONE, INC. (US) | 2023-05-23 | — | — | US | claimed |
| CN-113429307-A | Preparation method and application of stable isotope labeled glutamic acid and glutamic acid derivative | 深圳鼎邦生物科技有限公司 | 2021-09-24 | — | — | CN | claimed |
| WO-2021070957-A1 | BENZENE CONDENSED RING COMPOUND AND MEDICAL COMPOSITION CONTAINING SAME | 国立大学法人東北大学 | 2021-04-15 | — | — | WO | claimed |
| CN-112442009-A | Deuterated compounds and their use for treating cancer | 润佳（苏州）医药科技有限公司 | 2021-03-05 | — | — | CN | claimed |
| CN-112442010-A | Prodrug compound and application thereof in treating cancer | 润佳（苏州）医药科技有限公司 | 2021-03-05 | — | — | CN | claimed |
| US-4436729-A | ANTIBIOTICS, BACTERICIDES | SCHERING CORPORATION (US) | 1984-03-13 | — | — | US | claimed |
| US-4435388-A | Tylosin 20-imino-20-deoxo-4\"-acyl derivatives, pharmaceutical compositions and method of use | SCHERING CORPORATION (US) | 1984-03-06 | — | — | US | claimed |
| US-4402981-A | ANTIULCER AGENT | KALI-CHEMIE PHARMA, GMBH (DE) | 1983-09-06 | — | — | US | claimed |
| US-4401660-A | TYLOSINS; VETERINARY MEDICINE; PASTEURELLA; ANIMAL GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1983-08-30 | — | — | US | claimed |
| US-4359461-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1982-11-16 | — | — | US | claimed |
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | claimed |
| US-4142041-A | ANTICARCINOGENIC AGENTS | KOHJIN CO., LTD. (JP) | 1979-02-27 | — | — | US | claimed |
| US-4094976-A | ANTICOCCIDIAL CYCLICAMINO ETHANOLS AND ESTERS THEREOF | MERCK & CO., INC. (US) | 1978-06-13 | — | — | US | claimed |
| US-3989835-A | Method of using 6-substituted amino phenyl-2,3,5,6-tetra-hydro[2,1-b]thiazoles for controlling gastrointestinal nematodes | AMERICAN CYANAMID COMPANY (US) | 1976-11-02 | — | — | US | claimed |
| US-3953596-A | 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals | ICI UNITED STATES INC. (US) | 1976-04-27 | — | — | US | claimed |