Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.61 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.61 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.61 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.61 |
| ▸ | CFD | P00746 | 7/20 | 0.60 |
| ▸ | TPSB2 | P20231 | 4/20 | 0.60 |
| ▸ | F11 | P03951 | 4/20 | 0.60 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.60 |
| ▸ | PLG | P00747 | 1/20 | 0.60 |
| ▸ | PLAU | P00749 | 1/20 | 0.60 |
| ▸ | F7 | P08709 | 1/20 | 0.60 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22654317 | 0.89 | ABCB11 (0.54) | PTGER1PTGER4PTGER3PTGER2CFD | |
| SCHEMBL11092098 | 0.88 | CFD (0.51) | PTGER1PTGER4PTGER3PTGER2CFD | |
| SCHEMBL1007508 | 0.85 | CFD (0.68) | PTGER1PTGER4PTGER3PTGER2CFD | |
| SCHEMBL31757965 | 0.85 | CFD (0.68) | PTGER1PTGER4PTGER3PTGER2CFD | |
| SCHEMBL10591847 | 0.83 | FABP4 (0.72) | PTGER1PTGER4PTGER3PTGER2CFD | |
| SCHEMBL8714342 | 0.83 | TSHR (0.55) | PTGER1PTGER4PTGER3PTGER2CFD | |
| SCHEMBL11095059 | 0.80 | CXCL8 (0.56) | PTGER1PTGER4PTGER3PTGER2CFD | |
| SCHEMBL11828242 | 0.80 | MAPT (0.64) | HTR1ADRD2MAPTMAPK1TDP1 | |
| SCHEMBL5017858 | 0.79 | FABP4 (0.59) | PTGER1PTGER4PTGER3PTGER2CFD | |
| SCHEMBL9352062 | 0.78 | PTGER1 (0.59) | PTGER1FOLH1MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |