SCHEMBL11095391

SCHEMBL11095391

Fc1ccc(-c2[c]ccc(Cl)c2F)cc1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PTGS2 P35354 1/20 0.32
TXN P10599 1/20 0.30
TYMP P19971 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8210186 0.79 RPA1 (0.40) PTGS2
SCHEMBL4658503 0.79 MAOB (0.32) NPC1RAB9APTGS2
SCHEMBL9650469 0.77 PTGS2 (0.31) PTGS2
SCHEMBL2012242 0.76 MAPK1 (0.38) NPC1TP53TSHRRAB9ASMN1; SMN2
SCHEMBL8325384 0.76 NPC1 (0.32) NPC1TP53TSHRRAB9ASMN1; SMN2
SCHEMBL17514581 0.76 NISCH (0.38) NPC1TP53RAB9ASMN1; SMN2
SCHEMBL9728993 0.73 TYMP (0.38) NPC1TP53TSHRRAB9ASMN1; SMN2
SCHEMBL407446 0.73
SCHEMBL17514970 0.73
SCHEMBL3121614 0.73 KIF11 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0028355-B1 1,2-OXAZOLYLALKYL CARBAMATES, THEIR PREPARATION, THEIR USE AS HERBICIDES, AND HERBICIDES BASF Aktiengesellschaft (DE) 1984-05-09 EP disclosed