Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096701 | 0.88 | ALDH1A1 (0.63) | ALDH1A1TP53RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3077888 | 0.87 | RAB9A (0.62) | ALDH1A1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL2153557 | 0.82 | SMN1; SMN2 (0.58) | ALDH1A1TP53RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6358445 | 0.81 | MEN1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL247591 | 0.80 | CES2 (0.65) | ALDH1A1TP53RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6852259 | 0.79 | HPGD (0.60) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2381182 | 0.79 | PARP1 (0.55) | ALDH1A1RAB9ASMN1; SMN2KMT2ATDP1 | |
| SCHEMBL230930 | 0.79 | ALDH1A1 (0.63) | ALDH1A1TP53RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL29612638 | 0.79 | ALDH1A1 (0.63) | ALDH1A1TP53RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL20513003 | 0.78 | F2 (0.44) | ALDH1A1TP53RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456565-A | BY REACTING ANHYDRIDE WITH ANHYDROUS HYDROCYANIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1984-06-26 | — | — | US | claimed |
| US-4284584-A | REACTING AN ANHYDRIDE WITH AN ALKALI METAL CYANIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | claimed |
| US-4238412-A | CYANATION OF THE ANHYDRIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | claimed |
| US-4284584-A | REACTING AN ANHYDRIDE WITH AN ALKALI METAL CYANIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |
| US-4238412-A | CYANATION OF THE ANHYDRIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| US-3966728-A | ANTIPEPTIC ULCER ACTIVITY | NIPPON SHINYAKU CO., LTD. (JA) | 1976-06-29 | — | — | US | disclosed |