Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299008 | 0.78 | ENPP2 (0.57) | NPC1RAB9ASMN1; SMN2MAPTPDE3B | |
| SCHEMBL11099792 | 0.78 | MEN1 (0.54) | NPC1RAB9AMAPTPDE3BPDE3A | |
| SCHEMBL11096275 | 0.77 | PDE3B (0.55) | MAPTPDE3BPDE3AKMT2AMEN1 | |
| SCHEMBL2533488 | 0.74 | TSHR (0.84) | NPC1RAB9AMAPTPDE3BPDE3A | |
| SCHEMBL11099214 | 0.73 | KMT2A (0.49) | NPC1RAB9ASMN1; SMN2MAPTPDE3B | |
| SCHEMBL5326670 | 0.73 | LMNA (0.58) | MAPTKMT2AMEN1ALOX15TSHR | |
| SCHEMBL2532397 | 0.72 | LMNA (0.78) | MAPTKMT2AMEN1ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL28701756 | 0.70 | LMNA (0.75) | MAPTKMT2AMEN1ALOX15TSHR | |
| SCHEMBL19186987 | 0.70 | KMT2A (0.70) | NPC1RAB9ASMN1; SMN2MAPTPDE3B | |
| SCHEMBL1752819 | 0.69 | RAB9A (0.62) | NPC1RAB9APKMSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122419-A2 | Substituted 3-mercaptopyridazines, their 3-alkylthio derivatives and processes for their preparation | A. Nattermann & Cie. GmbH (DE) | 1984-10-24 | — | — | EP | disclosed |