Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | ADH5 | P11766 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299008 | 0.81 | ENPP2 (0.57) | MEN1ALOX15TSHRKMT2APDE3B | |
| SCHEMBL11097731 | 0.78 | NPC1 (0.50) | MEN1ALOX15TSHRKMT2APDE3B | |
| SCHEMBL2533488 | 0.77 | TSHR (0.84) | MEN1ALOX15TSHRKMT2APDE3B | |
| SCHEMBL11099214 | 0.77 | KMT2A (0.49) | MEN1ALOX15TSHRKMT2APDE3B | |
| SCHEMBL2532397 | 0.75 | LMNA (0.78) | MEN1ALOX15TSHRKMT2ALMNA | |
| SCHEMBL11100630 | 0.75 | CYP11B1 (0.57) | MAPTCYP3A4 | |
| SCHEMBL696731 | 0.74 | LMNA (0.64) | MEN1ALOX15TSHRKMT2ALMNA | |
| SCHEMBL11101040 | 0.74 | PDE3B (0.57) | MEN1ALOX15TSHRKMT2APDE3B | |
| Hydrochloric Acid SCHEMBL28701756 | 0.73 | LMNA (0.75) | MEN1ALOX15TSHRKMT2ALMNA | |
| SCHEMBL11104630 | 0.73 | CYP3A4 (0.34) | MEN1ALOX15TSHRKMT2APDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122419-A2 | Substituted 3-mercaptopyridazines, their 3-alkylthio derivatives and processes for their preparation | A. Nattermann & Cie. GmbH (DE) | 1984-10-24 | — | — | EP | disclosed |