Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.48 |
| ▸ | ADH5 | P11766 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099792 | 0.77 | MEN1 (0.54) | KMT2AMEN1ALOX15TSHRPDE3B | |
| SCHEMBL11101040 | 0.75 | PDE3B (0.57) | KMT2AMEN1ALOX15TSHRPDE3B | |
| SCHEMBL11097731 | 0.73 | NPC1 (0.50) | KMT2AMEN1ALOX15TSHRPDE3B | |
| SCHEMBL2533488 | 0.73 | TSHR (0.84) | KMT2AMEN1ALOX15TSHRPDE3B | |
| SCHEMBL19186987 | 0.72 | KMT2A (0.70) | KMT2AMEN1ALOX15TSHRPDE3B | |
| SCHEMBL2532397 | 0.71 | LMNA (0.78) | KMT2AMEN1ALOX15TSHRADH5 | |
| SCHEMBL7299008 | 0.71 | ENPP2 (0.57) | KMT2AMEN1ALOX15TSHRPDE3B | |
| SCHEMBL11096275 | 0.70 | PDE3B (0.55) | KMT2AMEN1ALOX15TSHRPDE3B | |
| SCHEMBL6744620 | 0.70 | RAB9A (0.47) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL171705 | 0.69 | LMNA (0.64) | KMT2AMEN1ALOX15TSHRADH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122419-A2 | Substituted 3-mercaptopyridazines, their 3-alkylthio derivatives and processes for their preparation | A. Nattermann & Cie. GmbH (DE) | 1984-10-24 | — | — | EP | disclosed |