Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11164570 | 0.84 | ALDH1A1 (0.57) | GAAKDM4EALDH1A1MAPTPTGDR2 | |
| SCHEMBL11093981 | 0.83 | TLR7 (0.49) | GAAALDH1A1TSHRKMT2APLA2G1B | |
| SCHEMBL10227 | 0.81 | CACNA1G (0.46) | GAAKDM4EPTGDR2PLA2G2A | |
| SCHEMBL11093449 | 0.81 | ALDH1A1 (0.48) | GAAKDM4EALDH1A1TSHRMEN1 | |
| SCHEMBL8954292 | 0.81 | ALDH1A1 (0.49) | KDM4EALDH1A1PTGDR2MEN1KMT2A | |
| SCHEMBL11092577 | 0.80 | CASR (0.47) | KDM4EALDH1A1PLA2G2A | |
| SCHEMBL11098913 | 0.80 | CCR2 (0.50) | GAAKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL6227119 | 0.80 | ALDH1A1 (0.43) | GAAALDH1A1MEN1KMT2APLA2G2A | |
| SCHEMBL7048392 | 0.80 | AGTR1 (0.44) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5331525 | 0.79 | AGTR1 (0.42) | GAAALDH1A1MEN1KMT2APLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028834-B1 | IMIDAZOLE-5-ACETIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-01-18 | — | — | EP | disclosed |
| US-4355040-A | Hypotensive imidazole-5-acetic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-10-19 | — | — | US | disclosed |