Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12459029 | 0.88 | CRHBP (0.52) | ALOX5TRPM4ALDH1A1HIF1ACYP1B1 | |
| SCHEMBL19821130 | 0.86 | MEN1 (0.49) | ALOX5ALDH1A1CRHBPCRHR2NQO1 | |
| SCHEMBL12459447 | 0.85 | MEN1 (0.47) | ALOX5ALDH1A1CRHBPCRHR2MEN1 | |
| SCHEMBL6545417 | 0.84 | CASP6 (0.48) | TRPM4ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL3923458 | 0.84 | GABRA1 (0.42) | ALOX5TRPM4ALDH1A1HIF1ACYP1B1 | |
| SCHEMBL6600451 | 0.83 | POLB (0.52) | TRPM4ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL10530767 | 0.83 | NQO1 (0.50) | ALOX5TRPM4ALDH1A1HIF1ACYP1B1 | |
| SCHEMBL22256374 | 0.80 | ALDH1A1 (0.37) | ALOX5TRPM4ALDH1A1HIF1ACYP1B1 | |
| SCHEMBL22658046 | 0.79 | TRPM4 (0.42) | TRPM4ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL20564544 | 0.79 | CYP1A2 (0.42) | TRPM4ALDH1A1HIF1ACYP1B1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111410967-B | Circular polarization luminous chiral nematic liquid crystal material and preparation method and application thereof | 国家纳米科学中心 | 2022-04-08 | — | — | CN | claimed |
| EP-3599234-B1 | STEREOSELECTIVE PROCESS | BOEHRINGER INGELHEIM INT (DE) | 2021-04-07 | — | — | EP | claimed |
| CN-111410967-A | Circular polarization luminous chiral nematic liquid crystal material and preparation method and application thereof | 国家纳米科学中心 | 2020-07-14 | — | — | CN | claimed |
| EP-3599234-A1 | STEREOSELECTIVE PROCESS | Boehringer Ingelheim International GmbH (DE) | 2020-01-29 | — | — | EP | claimed |
| US-10189776-B2 | Stereoselective process | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-01-29 | — | — | US | claimed |
| US-20180258031-A1 | STEREOSELECTIVE PROCESS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-09-13 | — | — | US | claimed |
| US-8084611-B2 | Process for preparing tetrahydroquinoline derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-12-27 | — | — | US | claimed |
| EP-2154132-A1 | A process for preparing tetrahydroquinoline derivatives | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-02-17 | — | — | EP | claimed |
| US-20090292125-A1 | PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-26 | — | — | US | claimed |
| EP-2007728-A1 | A PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-12-31 | — | — | EP | claimed |
| WO-2007116922-A1 | A PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-10-18 | — | — | WO | claimed |
| US-6339159-B1 | REACTING AN ALDEHYDE COMPOUND, AN AMINO COMPOUND AND HYDROGEN CYANATE IN THE PRESENCE OF A CHIRAL ZIRCONIUM CATALYST OBTAINED BY MIXING ZIRCONIUM ALKOXIDE WITH OPTICALLY ACTIVE BINAPHTHOL COMPOUND TO FORM ALPHA-AMINONITRILE | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2002-01-15 | — | — | US | claimed |
| CN-116284143-B | Platinum complex and organic electroluminescent device comprising same | 季华恒烨(佛山)电子材料有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-115448961-B | Binuclear ionic complex and preparation method and application thereof | 中化学科学技术研究有限公司 | 2024-09-06 | — | — | CN | disclosed |
| US-12060362-B2 | Inhibitors of glucose transporters (GLUTs) | LEAD DISCOVERY CENTER GMBH (DE) | 2024-08-13 | — | — | US | disclosed |
| CN-116284143-A | Platinum complex and organic electroluminescent device comprising same | 季华恒烨(佛山)电子材料有限公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2007124383-A2 | 1,1'-BINAPHTHYL-BASED INHIBITORS OF NAD+-DEPENDENT DEACETYLASE ACTIVITY AND SIR2-FAMILY MEMBERS | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007124383-A2 | 1,1'-BINAPHTHYL-BASED INHIBITORS OF NAD+-DEPENDENT DEACETYLASE ACTIVITY AND SIR2-FAMILY MEMBERS | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007116922-A1 | A PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-10-18 | — | — | WO | disclosed |
| US-6339159-B1 | REACTING AN ALDEHYDE COMPOUND, AN AMINO COMPOUND AND HYDROGEN CYANATE IN THE PRESENCE OF A CHIRAL ZIRCONIUM CATALYST OBTAINED BY MIXING ZIRCONIUM ALKOXIDE WITH OPTICALLY ACTIVE BINAPHTHOL COMPOUND TO FORM ALPHA-AMINONITRILE | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2002-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12060362-B2 | Inhibitors of glucose transporters (GLUTs) | SLC2A1, SLC2A3, SLC2A4 | ALOX5 2707/4885TRPM4 2148/4885ALDH1A1 364/4885 |
| US-20090292125-A1 | PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | PCSK9, LSS, DHCR7 | ALOX5 293/4885TRPM4 2123/4885ALDH1A1 2381/4885 |
| US-10189776-B2 | Stereoselective process | CYP4A11, CYP4B1, CYP3A4 | ALOX5 642/4885TRPM4 1670/4885ALDH1A1 316/4885 |
| US-20180258031-A1 | STEREOSELECTIVE PROCESS | CYP4A11, CYP4B1, CYP3A4 | ALOX5 642/4885TRPM4 1670/4885ALDH1A1 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.