Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1109931 | 0.84 | ALOX5 (0.46) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL29434773 | 0.78 | CYP2A6 (0.48) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL12459029 | 0.77 | CRHBP (0.52) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL19821130 | 0.75 | MEN1 (0.49) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL12459447 | 0.74 | MEN1 (0.47) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL32663653 | 0.74 | GPR84 (0.36) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL6545417 | 0.74 | CASP6 (0.48) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL6600451 | 0.72 | POLB (0.52) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL10530767 | 0.72 | NQO1 (0.50) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL31491192 | 0.71 | MEN1 (0.60) | ALDH1A1KDM4EMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658774-B | Synthesis method of novel chiral nitrobinaphthol and derivatives thereof | 中国科学院青岛生物能源与过程研究所 | 2020-11-27 | — | — | CN | claimed |
| CN-108658774-B | Synthesis method of novel chiral nitrobinaphthol and derivatives thereof | 中国科学院青岛生物能源与过程研究所 | 2020-11-27 | — | — | CN | disclosed |
| US-7517828-B2 | Chiral broensted acid catalyst for asymmetric synthesis and method of asymmetric synthesis with the catalyst | TOAGOSEI CO., LTD. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20060276329-A1 | Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst | TOAGOSEI CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1623971-A1 | ASYMMETRIC-SYNTHESIS CATALYST BASED ON CHIRAL BROENSTED ACID AND METHOD OF ASYMMETRIC SYNTHESIS WITH THE CATALYST | TOAGOSEI CO., LTD. (JP) | 2006-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276329-A1 | Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst | LSS, COASY, FASN | GABRA1 520/4885GABRB1 1028/4885GABRA2 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.