Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR6 | O00574 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11133855 | 0.94 | ALDH1A1 (0.46) | MEN1KMT2AMAPTCHEK1TSHR | |
| SCHEMBL11097656 | 0.94 | CXCR4 (0.45) | MEN1KMT2AMAPTCHEK1TSHR | |
| SCHEMBL11095527 | 0.93 | CTSD (0.43) | CXCR6MEN1KMT2AEPHX2CTSD | |
| SCHEMBL11096572 | 0.93 | DRD2 (0.45) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11097236 | 0.86 | MAPT (0.45) | MEN1KMT2AMAPTCHEK1TSHR | |
| SCHEMBL11093919 | 0.86 | UBE2M (0.43) | CXCR6MEN1KMT2AMAPTTSHR | |
| SCHEMBL11261854 | 0.85 | MEN1 (0.56) | MEN1KMT2AEPHX2MAPT | |
| SCHEMBL11092428 | 0.85 | DRD2 (0.52) | CXCR6TSHR | |
| SCHEMBL11100992 | 0.85 | ALDH1A1 (0.52) | CXCR6MEN1KMT2AMAPTSIGMAR1 | |
| SCHEMBL11096164 | 0.84 | CXCR6 (0.48) | CXCR6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | claimed |
| EP-0031219-B1 | ANILINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | disclosed |