Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099758 | 0.94 | CXCR6 (0.46) | NPC1RAB9ACHEK1MEN1KMT2A | |
| SCHEMBL11133855 | 0.93 | ALDH1A1 (0.46) | NPC1RAB9ACHEK1MEN1KMT2A | |
| SCHEMBL11095527 | 0.92 | CTSD (0.43) | NPC1RAB9ACHEK1MEN1KMT2A | |
| SCHEMBL11096572 | 0.92 | DRD2 (0.45) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11266729 | 0.85 | ACKR3 (0.51) | TRPV1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11097236 | 0.85 | MAPT (0.45) | NPC1RAB9ACHEK1MEN1KMT2A | |
| SCHEMBL11097949 | 0.85 | DRD2 (0.51) | CXCR4L3MBTL1LTA4HALPLALPI | |
| SCHEMBL11093919 | 0.85 | UBE2M (0.43) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11270191 | 0.84 | CXCR4 (0.47) | CXCR4L3MBTL1LTA4HALPLALPI | |
| SCHEMBL11089660 | 0.83 | HCRTR1 (0.53) | CXCR4MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | claimed |
| EP-0031219-B1 | ANILINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | disclosed |