Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ADH5 | P11766 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096275 | 0.81 | PDE3B (0.55) | PDE3BPDE3AMEN1KMT2AALOX15 | |
| SCHEMBL11096605 | 0.78 | PDE3B (0.52) | PDE3BPDE3AMEN1KMT2AALOX15 | |
| SCHEMBL11101037 | 0.78 | PDE3B (0.52) | PDE3BPDE3AMEN1KMT2AALOX15 | |
| SCHEMBL11102889 | 0.77 | PDE3B (0.38) | PDE3BPDE3AADH5MAPTLMNA | |
| SCHEMBL11099862 | 0.76 | PDE3B (0.50) | PDE3BPDE3AMEN1KMT2AALOX15 | |
| SCHEMBL11104830 | 0.76 | PDE3B (0.36) | PDE3BPDE3AKMT2AALOX15ADH5 | |
| SCHEMBL11099214 | 0.75 | KMT2A (0.49) | PDE3BPDE3AMEN1KMT2AALOX15 | |
| SCHEMBL11096661 | 0.75 | ADH5 (0.48) | PDE3BPDE3AADH5CYP3A4ALDH1A1 | |
| SCHEMBL11100354 | 0.74 | PDE3B (0.48) | PDE3BPDE3AMEN1KMT2AALOX15 | |
| SCHEMBL11099792 | 0.74 | MEN1 (0.54) | PDE3BPDE3AMEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122419-A2 | Substituted 3-mercaptopyridazines, their 3-alkylthio derivatives and processes for their preparation | A. Nattermann & Cie. GmbH (DE) | 1984-10-24 | — | — | EP | disclosed |