Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670560 | 0.83 | KDM4E (0.52) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL1110103 | 0.82 | FOLH1 (0.43) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL6362640 | 0.75 | CYP1A2 (0.53) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL10909445 | 0.75 | CDC25B (0.60) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL25986589 | 0.75 | MAPT (0.62) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL38665356 | 0.75 | MAPT (0.62) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL50624 | 0.74 | ALDH1A1 (0.56) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL19865344 | 0.74 | CYP1A2 (0.41) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL13209727 | 0.74 | CNR2 (0.49) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL13209718 | 0.74 | ALDH1A1 (0.47) | MAPTALDH1A1HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279291-B1 | COFERONS AND METHODS OF MAKING AND USING THEM | UNIV CORNELL (US) | 2019-07-03 | — | — | EP | disclosed |
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-20150105553-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-16 | — | — | US | disclosed |
| US-8853185-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2014-10-07 | — | — | US | disclosed |
| US-20110263688-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | PURDUE RESEARCH FOUNDATION (US) | 2011-10-27 | — | — | US | disclosed |
| EP-2279291-A2 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009126290-A2 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009126290-A2 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2009-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105553-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | MYOF, TNFSF11, F13B | MAPT 2555/4885ALDH1A1 2898/4885HPGD 2895/4885 |
| US-20110263688-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | MYOF, FTH1, TFRC | MAPT 3431/4885ALDH1A1 3614/4885HPGD 1780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.