Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Acetone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL7902886 | 1.00 | — | — | |
| Acetone SCHEMBL9421219 | 1.00 | LMNA (0.86) | — | |
| Acetone SCHEMBL2722662 | 1.00 | LMNA (0.86) | — | |
| Acetone SCHEMBL30579765 | 1.00 | — | — | |
| Acetone SCHEMBL2722666 | 1.00 | LMNA (0.86) | — | |
| Acetone SCHEMBL2723172 | 1.00 | LMNA (0.86) | — | |
| Acetone SCHEMBL362166 | 1.00 | — | — | |
| Acetone SCHEMBL3501755 | 1.00 | — | — | |
| Acetone SCHEMBL2726164 | 1.00 | — | — | |
| Acetone SCHEMBL11640815 | 0.94 | LMNA (0.75) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484578-B | A kind of method of esomeprazole impurity preparation | 珠海润都制药股份有限公司 | 2019-03-26 | — | — | CN | claimed |
| CN-106317150-B | A kind of crystal-form compound of anti-tumor drug and preparation method thereof | 山东罗欣药业集团股份有限公司 | 2019-02-15 | — | — | CN | claimed |
| CN-108524951-A | A kind of Sorafenib nanometer formulation with liver tumour targeting | 南昌大学第二附属医院 | 2018-09-14 | — | — | CN | claimed |
| CN-108484578-A | A kind of method prepared by esomeprazole impurity | 珠海润都制药股份有限公司 | 2018-09-04 | — | — | CN | claimed |
| CN-108166261-A | A kind of environment-friendly watertight washes waterproofing agent and preparation method thereof | 江苏尼美达科技有限公司 | 2018-06-15 | — | — | CN | claimed |
| CN-106588881-A | Method for preparing Vandetanib compound used for Vandetanib composition dry suspension serving as anti-tumor drug | 临沂草之美医药科技有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-106317150-A | Crystalline compound for antitumor medicines and method for preparing crystalline compound | 山东罗欣药业集团股份有限公司 | 2017-01-11 | — | — | CN | claimed |
| CN-102558431-B | Preparation method of tumor developer folate--poly hydroxyethyl acrylate-diethylenetriamine pentaacetic acid | JIANGSU INST OF NUCLEAR MED | 2013-07-17 | — | — | CN | claimed |
| CN-102526775-B | 99Tcm-labeled folate-polyhydroxyethyl acrylate-diethylenetriaminepentaacetic acid and preparation method thereof | JIANGSU INST OF NUCLEAR MED | 2013-03-13 | — | — | CN | claimed |
| CN-102558431-A | Preparation method of tumor developer folate--poly hydroxyethyl acrylate-diethylenetriamine pentaacetic acid | JIANGSU INST NUCLEAR MEDICINE | 2012-07-11 | — | — | CN | claimed |
| CN-101921740-A | Method for preparing carboxypeptidase B and composition of carboxypeptidase B | JIANGSU WANBANG BIOCHEMICAL MEDICINE CO LTD | 2010-12-22 | — | — | CN | claimed |
| CN-101869113-A | Cyclodextrin inclusion compound of rodents sterilant and preparation method thereof | INST PLANT PROTECTION IPP CAAS | 2010-10-27 | — | — | CN | claimed |
| CN-101310742-A | Tibetan medicine Honglian extract and use thereof | UNIV LANZHOU (CN) | 2008-11-26 | — | — | CN | claimed |
| CN-101002826-A | Tibetan herb medicine Tangute Qinglan Extractive, and its application | UNIV LANZHOU (CN) | 2007-07-25 | — | — | CN | claimed |
| CN-1899353-A | Compound Chinese medicine injection for supplementing qi and recovering pulse and its preparing method | LUO YIMIN (CN) | 2007-01-24 | — | — | CN | claimed |
| CN-1281287-C | Therapeutic film-forming compositions and therapeutic systems thereof | ISRAEL DVORETZKY (US) | 2006-10-25 | — | — | CN | claimed |
| CN-1514706-A | Therapeutic film-forming compositions and therapeutic systems thereof | ��˹���������дĻ� | 2004-07-21 | — | — | CN | claimed |
| CN-1425291-A | Alpha-ternary thiophene cyclo-dextrin or cyclo-dextrin biological clathrate and preparing method | UNIV HUANAN AGRICULTURE (CN) | 2003-06-25 | — | — | CN | claimed |
| CN-118271362-A | Preparation method of C5 phosphonate | 万华化学集团股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| US-3932482-A | CARDIOTONIC | STERLING DRUG INC. (US) | 1976-01-13 | — | — | US | disclosed |