SCHEMBL11112293

SCHEMBL11112293

CCCCCNc1nnco1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.39
KCNH3 Q9ULD8 1/20 0.36
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
DNM2 P50570 6/20 0.34
SOAT1 P35610 2/20 0.34
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15210309 0.71 ALDH1A1 (0.50) HTTALDH1A1
SCHEMBL3189851 0.70 TLR8 (0.40) ELANEKCNH3MAPTHTTNPSR1
SCHEMBL18493847 0.69 ALDH1A1 (0.54) HTTNPSR1ALDH1A1TSHR
SCHEMBL11535323 0.69 ELANE (0.43) ELANEKCNH3DNM2ALDH1A1
SCHEMBL1780408 0.68 KCNH2 (0.36) MAPTALDH1A1
SCHEMBL11665043 0.68 CYP3A4 (0.39) ELANEKCNH3NPSR1DNM2ALDH1A1
SCHEMBL11539500 0.68 DNM2 (0.44) ELANEKCNH3MAPTHTTNPSR1
SCHEMBL21144228 0.67 KCNH2 (0.39) MAPTALDH1A1
SCHEMBL21210736 0.67 KCNH2 (0.39) MAPTALDH1A1
SCHEMBL4611727 0.67 KCNH2 (0.39) MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017025396-A1 HERBICIDAL COMPOSITIONS COMPRISING N-(TETRAZOLE-5-YL)- OR N-(1,3,4- OXADIAZOLE-2-YL)ARYL AMIDES AND AN 3-ISOXAZOLIDINONE DERIVATIVE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-02-16 WO disclosed
WO-2017025396-A1 HERBICIDAL COMPOSITIONS COMPRISING N-(TETRAZOLE-5-YL)- OR N-(1,3,4- OXADIAZOLE-2-YL)ARYL AMIDES AND AN 3-ISOXAZOLIDINONE DERIVATIVE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-02-16 WO disclosed
EP-0107366-A1 Pyrrolidinone analogs and precursors ELI LILLY AND COMPANY (US) 1984-05-02 EP disclosed