SCHEMBL15210309

SCHEMBL15210309

CCCCCC(=O)Nc1nnco1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
LMNA P02545 2/20 0.47
POLB P06746 1/20 0.47
SMN1; SMN2 Q16637 5/20 0.45
HTT P42858 1/20 0.45
NPC1 O15118 3/20 0.43
GLA P06280 1/20 0.43
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
DEGS1 O15121 1/20 0.43
KMT2A Q03164 1/20 0.43
RAB9A P51151 3/20 0.43
HPGD P15428 1/20 0.43
XDH P47989 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CETP P11597 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18493847 0.95 ALDH1A1 (0.54) ALDH1A1LMNAPOLBSMN1; SMN2HTT
SCHEMBL7091214 0.75 LMNA (0.50) ALDH1A1LMNAPOLBSMN1; SMN2NPC1
SCHEMBL20942734 0.75 TSHR (0.43) ALDH1A1LMNAPOLBSMN1; SMN2MAPK1
SCHEMBL11544586 0.74 LMNA (0.46) ALDH1A1LMNAPOLBSMN1; SMN2NPC1
SCHEMBL11198290 0.73 ALDH1A1 (0.50) ALDH1A1LMNASMN1; SMN2NPC1RAB9A
SCHEMBL11538934 0.73 LMNA (0.48) ALDH1A1LMNAPOLBSMN1; SMN2NPC1
SCHEMBL1527363 0.72 LMNA (0.44) ALDH1A1LMNAPOLBSMN1; SMN2NPC1
SCHEMBL11112293 0.71 ELANE (0.39) ALDH1A1HTT
SCHEMBL2745420 0.70 CETP (0.56) ALDH1A1LMNAPOLBSMN1; SMN2L3MBTL1
SCHEMBL2744688 0.70 CETP (0.56) ALDH1A1LMNAPOLBSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11304418-B2 Substituted n-(-1,3,4-oxadiazole-2-yl)aryl carboxamides and the use thereof as herbicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT 2022-04-19 US disclosed
US-20210076680-A1 SUBSTITUTED N-(-1,3,4-OXADIAZOLE-2-YL)ARYL CARBOXAMIDES AND THE USE THEREOF AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-03-18 US disclosed
CN-105658067-B Herbicidal compositions containing N- (1,3, 4-oxadiazol-2-yl) -aryl carboxylic acid amides 拜耳作物科学股份公司 2020-07-31 CN disclosed
CN-105658067-B Herbicidal compositions containing N- (1,3, 4-oxadiazol-2-yl) -aryl carboxylic acid amides 拜耳作物科学股份公司 2020-07-31 CN disclosed
US-10556874-B2 N-(1,3,4-oxadiazol-2-yl)aryl carboxamide derivatives with herbicidal action BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-02-11 US disclosed
EP-3601242-A1 SUBSTITUTED N-(-1,3,4-OXADIAZOLE-2-YL)ARYL CARBOXAMIDES AND THE USE THEREOF AS HERBICIDES Bayer CropScience Aktiengesellschaft (DE) 2020-02-05 EP disclosed
US-10433553-B2 Salts of N-(1,3,4-oxadiazol-2-yl) aryl carboxylic acid amides and the use of same as herbicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-10-08 US disclosed
US-10111435-B2 Herbicidal compositions containing N-(1,3,4-oxadiazol-2-yl)-aryl carboxylic acid amides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-10-30 US disclosed
WO-2018177871-A1 SUBSTITUTED N-(-1,3,4-OXADIAZOLE-2-YL)ARYL CARBOXAMIDES AND THE USE THEREOF AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-10-04 WO disclosed
EP-3356336-A1 METHOD FOR SYNTHESIZING N-(1,3,4-OXADIAZOLE-2-YL)ARYL CARBOXAMIDES Bayer CropScience Aktiengesellschaft (DE) 2018-08-08 EP disclosed
EP-3060057-A1 HERBICIDAL COMPOSITIONS CONTAINING N-(1,3,4-OXADIAZOL-2-YL)-ARYL CARBOXYLIC ACID AMIDES Bayer CropScience Aktiengesellschaft (DE) 2016-08-31 EP disclosed
US-20160242419-A1 Herbicidal Compositions Containing N-(1,3,4-oxadiazol-2-yl)-aryl Carboxylic Acid Amides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-08-25 US disclosed
EP-3051947-A1 HERBICIDE-SAFENER COMPOSITIONS CONTAINING N-(1,3,4-OXADIAZOL-2-YL)ARYL CARBOXYLIC ACID AMIDES Bayer CropScience Aktiengesellschaft (DE) 2016-08-10 EP disclosed
CN-105658067-A Herbicidal compositions containing n-(1,3,4-oxadiazol-2-yl)-aryl carboxylic acid amides 拜耳作物科学股份公司 2016-06-08 CN disclosed
CN-105592699-A Herbicide-safener combination containing N- (1,3, 4-oxadiazol-2-yl) arylcarboxylic acid amides BAYER CROPSCIENCE AG 2016-05-18 CN disclosed
WO-2015059187-A1 HERBICIDAL COMPOSITIONS CONTAINING N-(1,3,4-OXADIAZOL-2-YL)-ARYL CARBOXYLIC ACID AMIDES BAYER CROPSCIENCE AG (DE) 2015-04-30 WO disclosed
WO-2015049225-A1 HERBICIDE-SAFENER COMPOSITIONS CONTAINING N-(1,3,4-OXADIAZOL-2-YL)ARYL CARBOXYLIC ACID AMIDES BAYER CROPSCIENCE AG (DE) 2015-04-09 WO disclosed
EP-2817298-A1 HERBICIDALLY ACTIVE 4-NITRO-SUBSTITUTED N-(TETRAZOL-5-YL)-, N-(TRIAZOL-5-YL)-, AND N-(1,3,4-OXADIAZOL-2-YL)ARYL CARBOXYLIC ACID AMIDES Bayer Intellectual Property GmbH (DE) 2014-12-31 EP disclosed
CN-104125948-A Herbicidally active 4-nitro-substituted n-(tetrazol-5-yl)-, n-(triazol-5-yl)-, and n-(1,3,4-oxadiazol-2-yl)aryl carboxylic acid amides BAYER IP GMBH 2014-10-29 CN disclosed
WO-2013124245-A1 HERBICIDALLY ACTIVE 4-NITRO-SUBSTITUTED N-(TETRAZOL-5-YL)-, N-(TRIAZOL-5-YL)-, AND N-(1,3,4-OXADIAZOL-2-YL)ARYL CARBOXYLIC ACID AMIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-08-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10111435-B2 Herbicidal compositions containing N-(1,3,4-oxadiazol-2-yl)-aryl carboxylic acid amides AADAC, DDT, DNPH1 ALDH1A1 84/4885LMNA 3651/4885POLB 3564/4885
US-10433553-B2 Salts of N-(1,3,4-oxadiazol-2-yl) aryl carboxylic acid amides and the use of same as herbicides AOX1, AOC2, NAT1 ALDH1A1 93/4885LMNA 3643/4885POLB 3556/4885
US-10556874-B2 N-(1,3,4-oxadiazol-2-yl)aryl carboxamide derivatives with herbicidal action NOX3, AOX1, NOX1 ALDH1A1 188/4885LMNA 2932/4885POLB 1875/4885
US-20160242419-A1 Herbicidal Compositions Containing N-(1,3,4-oxadiazol-2-yl)-aryl Carboxylic Acid Amides AADAC, DDT, DNPH1 ALDH1A1 84/4885LMNA 3651/4885POLB 3564/4885
US-11304418-B2 Substituted n-(-1,3,4-oxadiazole-2-yl)aryl carboxamides and the use thereof as herbicides DDT, NAT1, AADAC ALDH1A1 38/4885LMNA 3739/4885POLB 3809/4885
US-20210076680-A1 SUBSTITUTED N-(-1,3,4-OXADIAZOLE-2-YL)ARYL CARBOXAMIDES AND THE USE THEREOF AS HERBICIDES DDT, NAT1, AADAC ALDH1A1 38/4885LMNA 3739/4885POLB 3809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.