Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113792 | 0.83 | PARP1 (0.34) | SLC6A3RXRARXRBRXRG | |
| SCHEMBL11102648 | 0.78 | DRD2 (0.37) | — | |
| SCHEMBL11485763 | 0.74 | PARP1 (0.55) | RXRARXRBRXRG | |
| SCHEMBL10801507 | 0.72 | GAA (0.33) | RXRARXRBRXRG | |
| SCHEMBL11114385 | 0.71 | CXCR5 (0.36) | KDM4EALDH1A1HPGDRXRARXRB | |
| SCHEMBL11108245 | 0.70 | KMT2A (0.36) | — | |
| SCHEMBL10801217 | 0.67 | RXRA (0.32) | RXRARXRBRXRG | |
| SCHEMBL11109609 | 0.67 | ALDH1A1 (0.33) | KDM4EALDH1A1RXRARXRBRXRG | |
| SCHEMBL946263 | 0.66 | LMNA (0.49) | KDM4EALDH1A1 | |
| SCHEMBL11110558 | 0.66 | ALDH1A1 (0.35) | KDM4EALDH1A1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103173-A1 | Carbamic-acid esters, process and starting material for their preparation, parasiticides containing these esters as active products, as well as the use of such esters and agents in combating parasites | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-03-21 | — | — | EP | claimed |