Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114279 | 0.85 | ALDH1A1 (0.60) | ALDH1A1NFKB1MAPTMEN1KMT2A | |
| SCHEMBL11115121 | 0.84 | NFKB1 (0.55) | ALDH1A1NFKB1MAPTMEN1KMT2A | |
| SCHEMBL10686879 | 0.81 | MAPT (0.46) | ALDH1A1NFKB1MAPTMEN1KMT2A | |
| SCHEMBL3068206 | 0.80 | THRB (0.58) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL11114790 | 0.79 | CYP1A2 (0.45) | ALDH1A1NFKB1MAPTMEN1KMT2A | |
| SCHEMBL11110055 | 0.79 | ALDH1A1 (0.45) | ALDH1A1NFKB1MAPTMEN1KMT2A | |
| SCHEMBL13791527 | 0.79 | CASP3 (0.53) | ALDH1A1NFKB1MAPTMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL6014377 | 0.78 | CASP3 (0.51) | ALDH1A1NFKB1MAPTMEN1KMT2A | |
| SCHEMBL11116202 | 0.77 | ALDH1A1 (0.45) | ALDH1A1NFKB1MAPTMEN1KMT2A | |
| SCHEMBL5530443 | 0.76 | RAB9A (0.53) | ALDH1A1NFKB1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123700-A1 | Substituted picolinic acids, processes for their preparation, their use, and pharmaceutical preparations containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-11-07 | — | — | EP | disclosed |