Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 6/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 13/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11282578 | 0.84 | RXRA (0.43) | LTB4RFFAR4FFAR1 | |
| SCHEMBL8936259 | 0.79 | SLC6A1 (0.51) | FFAR1 | |
| SCHEMBL11117206 | 0.79 | PTGER1 (0.49) | LTB4RFFAR1 | |
| SCHEMBL5757559 | 0.77 | PTGER4 (0.51) | FFAR1 | |
| SCHEMBL11114869 | 0.77 | ALDH1A1 (0.42) | LTB4RFFAR4FFAR1 | |
| SCHEMBL11621301 | 0.76 | FFAR1 (0.60) | FFAR4FFAR1 | |
| SCHEMBL3030815 | 0.75 | ALDH1A1 (0.51) | FFAR1 | |
| SCHEMBL7905578 | 0.75 | FFAR1 (0.82) | FFAR4FFAR1 | |
| SCHEMBL11617007 | 0.72 | FFAR1 (0.59) | FFAR4FFAR1 | |
| SCHEMBL11115339 | 0.72 | NPC1 (0.43) | FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118867-A2 | Substituted 4,10-dihydro-10-oxothieno benzoxepins, a method of preparing the same and intermediate thereof and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1984-09-19 | — | — | EP | disclosed |