Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 3/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757559 | 0.91 | PTGER4 (0.51) | SLC6A1NR4A2PTPRCPTPN1NPC1 | |
| SCHEMBL11282578 | 0.83 | RXRA (0.43) | SMN1; SMN2KDM4EPTPRCPTPN1NPC1 | |
| SCHEMBL9586099 | 0.82 | SLC6A1 (0.46) | SLC6A1SMN1; SMN2KDM4EPTPRCPTPN1 | |
| SCHEMBL17643001 | 0.81 | SLC6A1 (0.44) | SLC6A1SMN1; SMN2KDM4EPTPRCPTPN1 | |
| SCHEMBL9026335 | 0.80 | RXRA (0.54) | SMN1; SMN2KDM4EPTPRCPTPN1RAB9A | |
| SCHEMBL3030815 | 0.80 | ALDH1A1 (0.51) | SLC6A1PTPRCNPC1RAB9AMEN1 | |
| SCHEMBL11114853 | 0.79 | LTB4R (0.56) | FFAR1 | |
| SCHEMBL11115339 | 0.79 | NPC1 (0.43) | SLC6A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL7831938 | 0.79 | NPC1 (0.54) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11114850 | 0.78 | AKR1C3 (0.47) | NPC1RAB9AMEN1KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031469-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |