Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11112172 | 0.90 | L3MBTL1 (0.42) | ALDH1A1TSHRFFAR1FFAR4NPC1 | |
| SCHEMBL10988964 | 0.87 | FFAR1 (0.40) | ALDH1A1TSHRFFAR1FFAR4NPC1 | |
| SCHEMBL11115339 | 0.86 | NPC1 (0.43) | ALDH1A1TSHRFFAR1FFAR4NPC1 | |
| SCHEMBL10984633 | 0.80 | ALDH1A1 (0.39) | ALDH1A1FFAR1NPC1RAB9ARXRA | |
| SCHEMBL11114850 | 0.78 | AKR1C3 (0.47) | ALDH1A1TSHRFFAR1NPC1RAB9A | |
| SCHEMBL9870392 | 0.78 | FFAR1 (0.50) | ALDH1A1TSHRFFAR1FFAR4ALOX5 | |
| SCHEMBL11118801 | 0.77 | KMT2A (0.42) | ALDH1A1TSHRNPC1RAB9AKDM4E | |
| SCHEMBL11114853 | 0.77 | LTB4R (0.56) | FFAR1FFAR4LTB4R | |
| SCHEMBL8936259 | 0.76 | SLC6A1 (0.51) | FFAR1NPC1RAB9AKDM4E | |
| SCHEMBL10985950 | 0.76 | RAB9A (0.42) | ALDH1A1TSHRFFAR1FFAR4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118867-A2 | Substituted 4,10-dihydro-10-oxothieno benzoxepins, a method of preparing the same and intermediate thereof and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1984-09-19 | — | — | EP | disclosed |