Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936259 | 0.91 | SLC6A1 (0.51) | NR4A2FFAR1SLC6A1PTPN1NPC1 | |
| SCHEMBL11282578 | 0.81 | RXRA (0.43) | FFAR1PTPN1NPC1RAB9AMEN1 | |
| SCHEMBL3030815 | 0.78 | ALDH1A1 (0.51) | FFAR1SLC6A1NPC1RAB9AMEN1 | |
| SCHEMBL26784498 | 0.77 | DHODH (0.49) | FFAR1DHODHPTPN1MEN1KMT2A | |
| SCHEMBL11114853 | 0.77 | LTB4R (0.56) | FFAR1 | |
| SCHEMBL11115339 | 0.77 | NPC1 (0.43) | FFAR1SLC6A1NPC1RAB9AMEN1 | |
| SCHEMBL11114850 | 0.76 | AKR1C3 (0.47) | FFAR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9026335 | 0.75 | RXRA (0.54) | PTPN1RAB9APTPRC | |
| SCHEMBL1760344 | 0.75 | TP53 (0.56) | PTGER4NR4A2FFAR1PTPN1PTPRC | |
| SCHEMBL10984633 | 0.75 | ALDH1A1 (0.39) | PTGER4FFAR1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663936-A1 | BIARYLOXYMETHYLARENE-CARBOXYLIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005000781-A1 | BIARYLOXYMETHYLARENE-CARBOXYLIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-01-06 | — | — | WO | disclosed |