Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113048 | 0.82 | KDM4E (0.51) | MAPK1L3MBTL1ALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL7273776 | 0.81 | L3MBTL1 (0.59) | MAPK1L3MBTL1SCN1ASCN2ASCN3A | |
| SCHEMBL9750661 | 0.73 | SMN1; SMN2 (0.46) | ACKR3L3MBTL1SCN1ASCN2ASCN3A | |
| SCHEMBL9750679 | 0.72 | SCN1A (0.49) | MAPK1L3MBTL1SCN1ASCN2ASCN3A | |
| Hydrochloric Acid SCHEMBL9750696 | 0.71 | SCN1A (0.48) | MAPK1L3MBTL1SCN1ASCN2ASCN3A | |
| SCHEMBL13219952 | 0.71 | ACKR3 (0.69) | ACKR3MAPK1L3MBTL1ALDH1A1TNFRSF1A | |
| SCHEMBL7276036 | 0.70 | KMT2A (0.49) | MAPK1L3MBTL1SCN1ASCN2ASCN3A | |
| Benzene SCHEMBL27454328 | 0.69 | SCN1A (0.44) | ACKR3MAPK1L3MBTL1SCN1ASCN2A | |
| Hydrochloric Acid SCHEMBL7266825 | 0.69 | KMT2A (0.48) | MAPK1SCN1ASCN2ASCN3AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9750666 | 0.69 | KMT2A (0.48) | MAPK1SCN1ASCN2ASCN3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041757-B1 | ETHYLENDIAMINE DERIVATIVES, PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND INTERMEDIATES FOR THEIR PREPARATION | Simes S.p.A. (IT) | 1984-11-07 | — | — | EP | disclosed |