Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KRAS | P01116 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.41 |
| ▸ | TUBB | P07437 | 6/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267000 | 0.86 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1KRASATML3MBTL1 | |
| SCHEMBL7273027 | 0.80 | CDK8 (0.47) | SMN1; SMN2ALDH1A1KRASATML3MBTL1 | |
| SCHEMBL7273155 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1KRASATML3MBTL1 | |
| SCHEMBL8937380 | 0.76 | KRAS (0.56) | SMN1; SMN2ALDH1A1KRASATML3MBTL1 | |
| SCHEMBL8937472 | 0.76 | KRAS (0.56) | SMN1; SMN2ALDH1A1KRASATML3MBTL1 | |
| SCHEMBL8937377 | 0.76 | KRAS (0.56) | SMN1; SMN2ALDH1A1KRASATML3MBTL1 | |
| SCHEMBL11115732 | 0.73 | ACKR3 (0.45) | SMN1; SMN2ALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL8719068 | 0.72 | PDE4A (0.49) | SMN1; SMN2ALDH1A1KRASATML3MBTL1 | |
| SCHEMBL8719072 | 0.72 | PDE4A (0.49) | SMN1; SMN2ALDH1A1KRASATML3MBTL1 | |
| SCHEMBL9750679 | 0.72 | SCN1A (0.49) | ALDH1A1L3MBTL1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988735-A | Ethylene diamine active cardiovascular therapy | SIMES (IT) | 1991-01-29 | — | — | US | disclosed |