Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823895 | 0.83 | CTSB (0.50) | ALDH1A1CTSBHCAR2KMT2AMAPK1 | |
| SCHEMBL7323732 | 0.79 | ALDH1A1 (0.49) | ALDH1A1CTSBHCAR2KMT2ASLC15A1 | |
| SCHEMBL142267 | 0.76 | CTSB (0.50) | CTSBSYK | |
| SCHEMBL8762963 | 0.75 | CTSB (0.51) | ALDH1A1CTSBHCAR2KMT2ASLC15A1 | |
| SCHEMBL9179158 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CTSBHCAR2KMT2ASLC15A1 | |
| SCHEMBL26161858 | 0.72 | CTSB (0.51) | ALDH1A1CTSBHCAR2KMT2AMAPK1 | |
| SCHEMBL11114587 | 0.72 | CTSB (0.43) | ALDH1A1CTSBHCAR2KMT2AMAPK1 | |
| SCHEMBL143177 | 0.71 | SYK (0.50) | CTSBSYK | |
| SCHEMBL42878 | 0.71 | CTSK (0.55) | ALDH1A1CTSB | |
| SCHEMBL2776839 | 0.71 | CTSK (0.55) | ALDH1A1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123951-A2 | Intermediates for thymosin alpha 1 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-11-07 | — | — | EP | disclosed |
| EP-0123950-A2 | Intermediates for thymosin alpha 1 and desacetylthymosin alpha 1 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-11-07 | — | — | EP | disclosed |