Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115639 | 0.82 | OPRM1 (0.41) | OPRM1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11117279 | 0.76 | OPRM1 (0.40) | OPRM1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10500141 | 0.74 | THRB (0.40) | MEN1KMT2A | |
| SCHEMBL11117024 | 0.69 | DCUN1D1 (0.46) | OPRM1MEN1KMT2A | |
| SCHEMBL10501298 | 0.67 | MMP1 (0.53) | MMP9MMP13ADAM17MEN1KMT2A | |
| SCHEMBL29362310 | 0.67 | BCHE (0.55) | BCHEACHE | |
| SCHEMBL11115913 | 0.67 | SLC18A3 (0.45) | OPRM1 | |
| SCHEMBL11114003 | 0.66 | OPRM1 (0.37) | MMP9OPRM1MEN1KMT2ANPC1 | |
| SCHEMBL11119013 | 0.66 | MEN1 (0.38) | OPRM1MEN1KMT2A | |
| SCHEMBL10499345 | 0.64 | HTR3E (0.40) | OPRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |