Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | CES2 | O00748 | 4/20 | 0.69 |
| ▸ | CES1 | P23141 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821225 | 0.93 | LMNA (0.69) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL1788851 | 0.84 | LMNA (0.67) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL19859915 | 0.84 | LMNA (0.67) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL18096456 | 0.84 | CES2 (0.67) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL145 | 0.82 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL901258 | 0.82 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL10665271 | 0.82 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL2025536 | 0.82 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL5833429 | 0.82 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL28120851 | 0.82 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9802952-B2 | Method and apparatus for the synthesis of dihydroartemisinin and artemisinin derivatives | Max-Plank-Gesellschaft zur Förderung der Wissenschaften e.v. (DE) | 2017-10-31 | — | — | US | disclosed |
| US-20160145265-A1 | METHOD AND APPARATUS FOR THE SYNTHESIS OF DIHYDROARTEMISININ AND ARTEMISININ DERIVATIVES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-05-26 | — | — | US | disclosed |
| EP-0114341-A2 | Dye-containing layer in a photopolymerisable composition, and process for obtaining relief and printing formes | BASF Aktiengesellschaft (DE) | 1984-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145265-A1 | METHOD AND APPARATUS FOR THE SYNTHESIS OF DIHYDROARTEMISININ AND ARTEMISININ DERIVATIVES | ADH1A, DHODH, DHPS | LMNA 1756/4885CES2 1696/4885CES1 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.